Training

1.Basic Chemistry On-site Course

1 day On-site Course For anyone who is new to analytical sciences or for anyone brave enough to admit to having forgotten some of the fundamental principles! This Basic Chemistry short course can be customised to suit the needs of particular groups of scientists and aims to cover the underpinning chemical principles of solution based and instrumental analytical science. Topics are customised to particular learner groups – typical one day course would cover 2 - 3 units of instruction, depending upon topics chosen. All topics contain worked examples & tutorial exercises. Meas...

2.Fundamental GC On-site course

1 day course for a group of up to 10 analysts - The basis of instrument hardware design - Sample preparation and the basics of the chromatographic process - Inlet systems, column and detector selection - Modes of chromatographic separation - Introduction to basic troubleshooting and maintenance

3.GC TroubleShooting Maintenance On-site

1 day course for a group of up to 10 analysts - The inlet system, column and detector - Troubleshooting the chromatogram is investigated through an evaluation of; * Inlet system optimisation – split/splitless, temperature, deactivation etc. * Detector optimisation * Changes to the chromatographic baseline – drifting, noisy etc. * Changes to chromatographic peak shape – broadening, splitting etc

4.GC Method Development On-site course

1 day course for up to 10 analysts - Establishing Method Objectives - Existing Information - what is known, what should be known - Chromatographic Theory Overview - Mechanisms of Separation - Equilibrium and the Distribution Constant Solute - Stationary Phase Interaction - Sample Preparation Protocols - Injection System Choice - spilt / splitless, on-column, direct, PTV, headspace. (Each of the above will be considered with reference to the physical properties of the analyte / matrix / solvent which govern choice) - Carrier Gas Choice - Column Choice (stationar...

5.GC Validation On-Site Course

1 day course for up to 10 analysts These courses have been designed for those who are developing and validating analytical methods within a regulated laboratory. These courses can help to overcome the steep learning curves associated with working in a regulated environment and can help the experienced analyst to develop and validate methods more quickly and concisely. The courses can be custom designed for your particular situation (often based on your existing validation SOP"s) and delivered by experts in the field of regulatory compliance within a number of industries assuring you t...

6.GC-MS for the Chromatographer On-site

1 day course for up to 10 analysts This course is designed to cover the basic operating and theoretical principles of gas chromatography using mass selective detection. It will be most useful to those who have a working knowledge of GC-MS but wish to understand the principles that govern the technique. Chromatographic Considerations: - Basic Principles of the Chromatographic Process - Partition Theory - Mechanisms of Gas Chromatography - The equilibrium / distribution constant & solute-stationary phase interactions - Temperature / Retention Relationship - Sample Introd...

7.GC-MS Interpretation On-site course

1 day course for up to 10 analysts This very popular course covers the principles of how to obtain good spectra – as well as having a host of tutor led exercises for crucial practice of interpretation skills and techniques. - Review of the chemistry of ions, electrons, radicals and isotopes - Principles of Electron Impact (EI) and Chemically Induced (CI) ionisation mechanisms - Fragmentation mechanisms including: - Homo and heterolytic fission, alpha-cleavage, McLafferty rearrangement etc. Interpretation rules including: - Isotopic abundances and normalisation, the Nitro...

8.Fundamentals of HPLC On-site course

1 day course for a group of up to 10 analysts The basis of instrument hardware design Modes of chromatographic separation – Reverse phase %B / ion pair reagents / optimising separations etc. Inter-relationship of resolution with other chromatographic descriptors Introduction to basic troubleshooting and maintenance Overview of current column chemistry

9.LC TroubleShooting Maintenance On-site

1 day course for up to 10 analysts - Common hardware problems associated with: mobile phase preparation, injector, pump, column and detector - Troubleshooting the chromatogram through an evaluation of; * The separation chemistry - pH and buffer strength effects * Changes to the chromatographic baseline – cyclical, fluctuating etc. * Changes to chromatographic peak shape – tailing, splitting etc. * Changes in the HPLC system operating pressure and analyte retention times and peak areas

10.HPLC Method Development On-site course

1 day course for up to 10 analysts - All our method development courses are designed in conjunction with our clients to ensure maximum relevance. All include simulated method developments to highlight critical issues and concepts. - Strategies and Implementation Protocols - Existing Information - what is known, what should be known - Separation Processes - Adsorption chromatography, reverse phase, ion suppression, ion exchange, gel permeation, gel filtration, affinity chromatography - Sample Preparation Protocols - Choice and Optimisation of Detection Technique - Opt...