Canvax Oxoglutarate Receptor 1 G0635-A

Oxoglutarate Receptor 1, ExpressMAX™ Human GPCR ORF Clones

Human Oxoglutarate (alpha-ketoglutarate) Receptor 1 (OXGR1) is encoded by the OXGR1 gene that is expressed in kidney and, to a lower extend, in placenta, not detected in brain tissues. It is a member of the GPCR family and is similar to the Purinergic P2Y receptors. OXGR1 is receptor for alpha-ketoglutarate, an intermediate in the citric acid cycle. Because OXGR1 activation did not affect cAMP levels and both inositol phosphate formation and calcium ion flux were found to be insensitive to pertussis toxin, this receptor seems to act exclusively through a G(q)-mediated pathway.

Main Features:

Native structure. Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.

Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)

Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).