Canvax Human IFITM3 (Interferon-induced transmembrane protein 3), 6xHis-GST tags PR0103

Human IFITM3 (Interferon-induced transmembrane protein 3), 6xHis-GST tags, high quality recombinant protein with proven performance in elisa, wb, ab production or protein array

Disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase).

Main Features:

Highest purity: free of interferences from other proteins or contaminants. Convenient: available in different sizes and tags. Cost avoidance: dry ice free of charge.

Includes: Includes for 50 µg: - 50 µg Recombinant Protein - Dry ice

Applications: ELISA. Western Blot. Antibody Production. Protein array.